Chitosan Has Been Shown In Recent Studies to Inhibit Bacterial Growth


Chitosan
Chitosan

Chitin, a polysaccharide derived from insects and crustaceans, is converted into chitosan by the deacetylation process. Chitosa has a wide range of advantageous effects, including antioxidant and antibacterial characteristics, despite the fact that there are little clinical investigations on its effects. A longer-term study is required to determine whether it is safe for humans, but it may also be successful in decreasing cholesterol levels. Despite being a naturally occurring polysaccharide, it is only found in shellfish because the chitin of crustaceans is subjected to an alkaline solution, usually sodium hydroxide. Additionally, this polymer is insoluble at physiological pH but soluble in aqueous acids. The distribution of acetyl groups and the extent of deacetylation determine the substance's physicochemical characteristics.

According to Coherent Market Insights the Chitosan Market Size, Share, Outlook, and Opportunity Analysis, 2020 - 2027

Although it has a rather large molecular weight, the mechanism underlying its antibacterial activity is yet unclear. Studies have nonetheless revealed that it prevents bacterial development. By adhering to the negatively charged elements of the bacterial cell wall, it can alter the permeability of bacterial cells. Additionally, due to its cationic properties, when combined with other food ingredients, this substance can change its antibacterial action.

Due to its large molecular weight and biodegradability, it might delay the release of the active ingredient and lessen negative effects associated with oral tablets. Furthermore, the controlled release of medications has been well researched for its microspheres. Its microspheres were created in this study by combining cationic chitosan with anionic chemicals. In addition, various medication kinds were put into the microspheres. Numerous pharmacological compounds were kept from dissolving in the cationic microspheres, and the protein medicines were shielded. Furthermore, the high molecular weight could shield protein medicines

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